Faculty

 

 

 

 

 

Richard A. Hesse, MS, PhD
Associate Professor
Director Diagnostic Virology
Phone: (785) 532-4457
Fax 785.532.4481
E-mail: dhesse@vet.ksu.edu

 

 

 

Service, Research and Teaching

My service, research and teaching responsibilities are closely interlinked. As Director of Diagnostic Virology I have the opportunity to isolate, identify and characterize emerging and re-emerging viral disease agents. Establishing collaborative ties with fellow scientists is integral to conducting research directed toward understanding the pathogenesis of diseases and developing innovative tools for rapid diagnosis. Additional collaboration with field veterinarians, producers and researchers fosters the development of efficacious vaccines and management control strategies of viral diseases. In the teaching environment I am further able to serve the community and university by sharing my experience with and knowledge of viral diseases and vaccines. Classroom instruction with veterinary and graduate students, workshops and seminars with field veterinarians and producers and noteworthy presentations at scientific meetings are all dynamic elements of my teaching responsibilities at KSU.

USDA Vaccine Licenses

Porcine Circovirus Vaccine, Type 2, Killed Baculovirus Vector, Code 19K5.RO
Conditional License. (2005).

Porcine Reproductive and Respiratory Syndrome (PRRS) Vaccine: Reproductive and Respiratory Forms of Disease. Modified Live Virus, Code 19T1.20 (1997).

Porcine Reproductive and Respiratory Syndrome (PRRS) Vaccine: Reproductive Disease. Modified Live Virus, Code 19T1.20 (1996).

Porcine Rotavirus (Bivalent) Transmissible Gastroenteritis Vaccine Clostridium Perfringens Type C Escherichia Coli Bacterin Toxoid, Modified Live and Killed Virus, Code 49B0.20. (1992).

Encephalomyelitis Influenza Vaccine, Eastern and Western, Killed Virus, Ehrlichia Risticii Tetanus Bacterin Toxoid, Code 4A35.4. (1992).

Encephalomyelitis Influenza Vaccine, Eastern and Western, Killed Virus, Tetanus Toxoid, Code 4835.00. (1992).

Encephalomyelitis Vaccine, Eastern and Western, Killed Virus, Tetanus Toxoid, Code 4865.00. (1992).

Porcine Rotavirus Transmissible Gastroenteritis Vaccine Clostridium Perfringens Type C Escherichia Coli Bacterin Toxoid, Modified Live and Killed Virus, Code 49B0.20. (1990).

Porcine Rotavirus Vaccine Clostridium Perfringens Type C Escherichia Coli Bacterin Toxoid, Killed Virus, Code 49C5.20. (1990).

Porcine Rotavirus Transmissible Gastroenteritis Vaccine, Modified live and Killed Virus, Code 19H7.20. (1990).

Porcine Rotavirus Vaccine, Killed Virus, Code 19E5.20. (1990).

Transmissible Gastroenteritis Vaccine, Modified Live Virus, Code 1961.00. (1990).

Patents

Porcine Reproductive and Respiratory Syndrome Virus Strains and Compositions (Pending).

U.S. Patent 5,866,401– Porcine Reproductive and Respiratory Syndrome Vaccine (Issued February 24, 1997).

Selected Publications

Y. Hoshino, S. Honma, R. Jones, J. Ross, N. Santos, J.Gentsch, A. Kapikian, and R. Hesse. 2005. A Porcine G9 Rotavirus Strain Shares Neutralization andVP7 Phylogenetic Sequence Linage 3 Characteristics with Contemporary Human G9 Rotavirus Strains. Virology 332:177-188

A. White, L. Hansen-Lardy, B. Brodersen, C. Kelling, R. Hesse, and G. Duhamel. 1998. Enhanced Immunohistochemical Detection of Infectious Agents in Formalin Fixed Embedded Tissues following Heat-mediated Antigen Retrieval.. JVDI 9:198-201

V. Cooper, R. Hesse, and A. Doster. 1997. Renal Lesions Associated With Experimental Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection. JVDI 9:198-201

J. Sur, V. Cooper, J. Galeota, R. Hesse, A. Doster, and F. Osorio. 1996. In Vivo Detection of Porcine Reproductive and Respiratory Syndrome Virus RNA by In Situ Hybridization at Different Times Post Infection. J Clin Micro, 34:2280-2286

V. Cooper, A. Doster, R. Hesse, and N. Harris. 1995. Porcine Reproductive and Respiratory Syndrome: NEB-1 PRRSV Did Not Potentiate Bacterial Pathogens. JVDI 7:313-320

W. Lu, G. Duhamel, Y. Hoshino, D. Benfield, and R. Hesse. 1995. Characterization of the Bovine Group A Rotavirus Strain Neonatal Calf Diarrhea Virus-Cody. J Clin Micro, 33:990-994

R. Hesse, L. Couture, S. Ellsworth, E. Dickinson, G. Duhamel, W. Lu, and D. Benfield. 1993. Production and Characterization of VP4/VP7 Reassortant Swine Rotaviruses Derived from Gottfried and OSU Parental Strains. AJVR, 54:1623 1629

R. Hesse and T.E. Toth. 1983. Effects of Bovine Parainfluenza 3 Virus on Phagocytosis and Phagosome Lysosome Fusion of Cultured Bovine Alveolar Macrophages. AJVR, 44: 1901 1907

P.B. Jahrling, R. Hesse, A.O. Anderson, and J.D. Gangemi. 1983. Opsonization of Alphaviruses in Hamsters. J Med Virol, 12: 1 16

T.E. Toth and R. Hesse. 1983. Replication of Five Bovine Respiratory Viruses in Cultured Bovine Alveolar Macrophages. Archives of Virology, 75: 219 224

T.E. Toth and R. Hesse. 1983. Elimination of Contaminating Bovine Viral Diarrhea Virus from Bovine Respiratory Syncytial Virus Stock. J Virol Meth, 6: 241 244

P.B. Jahrling, S. Smith, R.A.Hesse and J.B. Rhoderick, 1982. Pathogenesis of Lassa Virus Infection in Guinea Pigs. Inf and Imm. 37: 771 778

P.B. Jahrling, R.A.Hesse, J.B. Rhoderick, M.A. Elwell, and J.B. Moe. 1981. Pathogenesis of a Pichinde Virus Strain Adapted to Produce Lethal Infections in Guinea Pigs. Infect and Imm, 32: 872 880

P.B. Jahrling, R.A.Hesse, G.A. Eddy, K.M. Johnson, R.T. Callis, and E.L. Stephan. 1980. Lassa Virus Infection of Rhesus Monkeys: Pathogenesis and Treatment with Ribavirin. J Infect Dis, 141: 580 589

P.B. Jahrling, R.A.Hesse, and J.F. Metzger. 1978. Radioimmunoassay for Quantitation of Antibodies to Alphaviruses with Staphylococcal Protein A. J Clin Micro, 8: 54 60

P.B. Jahrling, G.B. Heisey, and R.A.Hesse. 1977. Evaluation of Vascular Clearance as a Marker for Virulence of Alphaviruses: Disassociation of Rapid Clearance with Low Virulence of Venezuelan Encephalitis Virus Strains in Guinea Pigs. Infect and Imm, 17: 356 360