Dr. Knepper received his Ph.D. in Biomedical Engineering from Case Western University in 1975, and his M.D. in 1976. His research interests include proteomics, renal function, epithelial function and biomedical engineering. He has published over 325 journal articles and book chapters on these subjects.

Dr. Knepper’s laboratory uses a systems biology approach to discover the fundamental mechanisms involved in regulation of the transport of water, urea and ions by the kidney, and to discover how these regulatory processes are altered in various clinically important fluid and electrolyte disorders. A major current emphasis is on regulatory systems involved in controlling water excretion by the kidney including mechanisms of aquaporin-2 regulation and the role of urea transporters in the urinary concentrating mechanism. Studies are also being conducted on the molecular basis of disordered renal NaCl transport in hypertension and congestive heart failure.

For more information about Dr. Knepper, please visit his webpage at
http://dir.nhlbi.nih.gov/staffpages/knepperm/index.asp

We are grateful that Dr. Knepper will present The Dr. Rudolf Clarenburg Lectureship in the College of Veterinary Medicine at Kansas State University.